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A New Strategy for Nucleic Acid Delivery and Protein Expression Using Biocompatible Nanohydrogels of Predefined Sizes

We have developed new formulations of nanohydrogels (NHGs) complexed with DNA devoid of cell toxicity, which, together with their tuned sizes, makes them of great interest for delivering DNA/RNA for foreign protein expression. Transfection results demonstrate that, unlike classical lipo/polyplexes,...

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Detalles Bibliográficos
Autores principales: Eswaran, Lakshmanan, Kazimirsky, Gila, Yehuda, Ronen, Byk, Gerardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058534/
https://www.ncbi.nlm.nih.gov/pubmed/36986821
http://dx.doi.org/10.3390/pharmaceutics15030961