DLin-MC3-Containing mRNA Lipid Nanoparticles Induce an Antibody Th2-Biased Immune Response Polarization in a Delivery Route-Dependent Manner in Mice

mRNA-based vaccines have made a leap forward since the SARS-CoV-2 pandemic and are currently used to develop anti-infectious therapies. If the selection of a delivery system and an optimized mRNA sequence are two key factors to reach in vivo efficacy, the optimal administration route for those vacci...

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Detalles Bibliográficos
Autores principales: Yavuz, Altan, Coiffier, Céline, Garapon, Cynthia, Gurcan, Serra, Monge, Claire, Exposito, Jean-Yves, Arruda, Danielle Campiol, Verrier, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058601/
https://www.ncbi.nlm.nih.gov/pubmed/36986871
http://dx.doi.org/10.3390/pharmaceutics15031009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058601/
https://www.ncbi.nlm.nih.gov/pubmed/36986871
http://dx.doi.org/10.3390/pharmaceutics15031009

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