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Monoterpenoid Epoxidiol Ameliorates the Pathological Phenotypes of the Rotenone-Induced Parkinson’s Disease Model by Alleviating Mitochondrial Dysfunction

Parkinson’s disease is the second most common neurodegenerative disease. Unfortunately, there is still no definitive disease-modifying therapy. In our work, the antiparkinsonian potential of trans-epoxide (1S,2S,3R,4S,6R)-1-methyl-4-(prop-1-en-2-yl)-7-oxabicyclo [4.1.0]heptan-2,3-diol (E-diol) was a...

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Detalles Bibliográficos
Autores principales: Aleksandrova, Yulia, Chaprov, Kirill, Podturkina, Alexandra, Ardashov, Oleg, Yandulova, Ekaterina, Volcho, Konstantin, Salakhutdinov, Nariman, Neganova, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058627/
https://www.ncbi.nlm.nih.gov/pubmed/36982914
http://dx.doi.org/10.3390/ijms24065842