Application of Minimal Physiologically-Based Pharmacokinetic Model to Simulate Lung and Trachea Exposure of Pyronaridine and Artesunate in Hamsters

A fixed-dose combination of pyronaridine and artesunate, one of the artemisinin-based combination therapies, has been used as a potent antimalarial treatment regimen. Recently, several studies have reported the antiviral effects of both drugs against severe acute respiratory syndrome coronavirus two...

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Detalles Bibliográficos
Autores principales: Kang, Dong Wook, Kim, Kyung Min, Kim, Ju Hee, Cho, Hea-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058671/
https://www.ncbi.nlm.nih.gov/pubmed/36986698
http://dx.doi.org/10.3390/pharmaceutics15030838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058671/
https://www.ncbi.nlm.nih.gov/pubmed/36986698
http://dx.doi.org/10.3390/pharmaceutics15030838

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