Identification of Potential Inhibitors for the Treatment of Alkaptonuria Using an Integrated In Silico Computational Strategy

Alkaptonuria (AKU) is a rare genetic autosomal recessive disorder characterized by elevated serum levels of homogentisic acid (HGA). In this disease, tyrosine metabolism is interrupted because of the alterations in homogentisate dioxygenase (HGD) gene. The patient suffers from ochronosis, fractures,...

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Detalles Bibliográficos
Autores principales: Zaib, Sumera, Rana, Nehal, Hussain, Nadia, Ogaly, Hanan A., Dera, Ayed A., Khan, Imtiaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058836/
https://www.ncbi.nlm.nih.gov/pubmed/36985595
http://dx.doi.org/10.3390/molecules28062623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058836/
https://www.ncbi.nlm.nih.gov/pubmed/36985595
http://dx.doi.org/10.3390/molecules28062623

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