Bioactive C21 Steroidal Glycosides from Euphorbia kansui Promoted HepG2 Cell Apoptosis via the Degradation of ATP1A1 and Inhibited Macrophage Polarization under Co-Cultivation

Euphorbia kansui is clinically used for the treatment of esophageal cancer, lung cancer, cancerous melanoma, asthma, pleural disorders, ascites, and pertussis, among other conditions. In this study, 12 steroids were obtained and identified from E. kansui, and cynsaccatol L (5), which showed the best...

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Detalles Bibliográficos
Autores principales: Feng, Xiaoyi, Li, Jianchun, Li, Hongmei, Chen, Xuanqin, Liu, Dan, Li, Rongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058894/
https://www.ncbi.nlm.nih.gov/pubmed/36985801
http://dx.doi.org/10.3390/molecules28062830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058894/
https://www.ncbi.nlm.nih.gov/pubmed/36985801
http://dx.doi.org/10.3390/molecules28062830

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