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Bioassay-Guided Alkaloids Isolation from Camellia sinensis and Colchicum luteum: In Silico and In Vitro Evaluations for Protease Inhibition

Bioassay-guided isolation from Camellia sinensis (Theaceae) and Colchicum luteum (Liliaceae) utilizing an in vitro model of protease assay revealed colchicine (1) and caffeine (2) from chloroform fractions, respectively. Their structures were validated using spectral techniques. The purified compoun...

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Detalles Bibliográficos
Autores principales: Aatif, Mohammad, Raza, Muhammad Asam, El Oirdi, Mohamed, Farhan, Mohd, Mumtaz, Muhammad Waseem, Hamayun, Muhammad, Ashraf, Adnan, Muteeb, Ghazala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058905/
https://www.ncbi.nlm.nih.gov/pubmed/36985431
http://dx.doi.org/10.3390/molecules28062459