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Metoprolol and CYP2D6: A Retrospective Cohort Study Evaluating Genotype-Based Outcomes

Metoprolol is a medication commonly utilized in select patients to achieve a reduction in heart rate, systolic blood pressure, or other indications. A majority of metoprolol metabolism occurs via CYP2D6. Decreased expression of the CYP2D6 enzyme increases the concentration of metoprolol. Current pha...

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Detalles Bibliográficos
Autores principales: Collett, Savannah, Massmann, Amanda, Petry, Natasha J., Van Heukelom, Joel, Schultz, April, Hellwig, Tadd, Baye, Jordan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058912/
https://www.ncbi.nlm.nih.gov/pubmed/36983598
http://dx.doi.org/10.3390/jpm13030416