Cargando…
Metoprolol and CYP2D6: A Retrospective Cohort Study Evaluating Genotype-Based Outcomes
Metoprolol is a medication commonly utilized in select patients to achieve a reduction in heart rate, systolic blood pressure, or other indications. A majority of metoprolol metabolism occurs via CYP2D6. Decreased expression of the CYP2D6 enzyme increases the concentration of metoprolol. Current pha...
Autores principales: | Collett, Savannah, Massmann, Amanda, Petry, Natasha J., Van Heukelom, Joel, Schultz, April, Hellwig, Tadd, Baye, Jordan F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058912/ https://www.ncbi.nlm.nih.gov/pubmed/36983598 http://dx.doi.org/10.3390/jpm13030416 |
Ejemplares similares
-
The effect of medication reconciliation on generating an accurate medication list in a pharmacogenomics practice
por: Petry, Natasha J., et al.
Publicado: (2022) -
Evolution of pharmacogenomic services and implementation of a multi-state pharmacogenomics clinic across a large rural healthcare system
por: Van Heukelom, Joel, et al.
Publicado: (2023) -
Examination of Metoprolol Pharmacokinetics and Pharmacodynamics Across CYP2D6 Genotype‐Derived Activity Scores
por: Thomas, Cameron D., et al.
Publicado: (2020) -
Impact of the CYP2D6 Genotype on Metoprolol Tolerance and Adverse Events in Elderly Chinese Patients With Cardiovascular Diseases
por: Chen, Jianqiao, et al.
Publicado: (2022) -
Effects of Flos carthami on CYP2D6 and on the Pharmacokinetics of Metoprolol in Rats
por: Liu, Gaofeng, et al.
Publicado: (2011)