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Extracellular Matrix Changes in Subcellular Brain Fractions and Cerebrospinal Fluid of Alzheimer’s Disease Patients

The brain’s extracellular matrix (ECM) is assumed to undergo rearrangements in Alzheimer’s disease (AD). Here, we investigated changes of key components of the hyaluronan-based ECM in independent samples of post-mortem brains (N = 19), cerebrospinal fluids (CSF; N = 70), and RNAseq data (N = 107; fr...

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Detalles Bibliográficos
Autores principales: Höhn, Lukas, Hußler, Wilhelm, Richter, Anni, Smalla, Karl-Heinz, Birkl-Toeglhofer, Anna-Maria, Birkl, Christoph, Vielhaber, Stefan, Leber, Stefan L., Gundelfinger, Eckart D., Haybaeck, Johannes, Schreiber, Stefanie, Seidenbecher, Constanze I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058969/
https://www.ncbi.nlm.nih.gov/pubmed/36982604
http://dx.doi.org/10.3390/ijms24065532