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Streptavidin-Saporin: Converting Biotinylated Materials into Targeted Toxins

Streptavidin-Saporin can be considered a type of ‘secondary’ targeted toxin. The scientific community has taken advantage of this conjugate in clever and fruitful ways using many kinds of biotinylated targeting agents to send saporin into a cell selected for elimination. Saporin is a ribosome-inacti...

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Detalles Bibliográficos
Autores principales: Ancheta, Leonardo R., Shramm, Patrick A., Bouajram, Raschel, Higgins, Denise, Lappi, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059012/
https://www.ncbi.nlm.nih.gov/pubmed/36977072
http://dx.doi.org/10.3390/toxins15030181