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Aspartate Reduces Liver Inflammation and Fibrosis by Suppressing the NLRP3 Inflammasome Pathway via Upregulating NS3TP1 Expression

Aspartate (Asp) can act on liver Kupffer cells, inhibit NOD-like receptor-P 3 (NLRP3) inflammatory bodies, and improve liver inflammation in acute hepatitis. However, the effect of Asp on the role of hepatic stellate cells (HSCs) in the pathogenesis of liver fibrosis in chronic liver injury remains...

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Detalles Bibliográficos
Autores principales: Zhou, Li, Zhao, Jing, Han, Ming, Ma, Anlin, Yang, Song, Zeng, Yilan, Cheng, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059041/
https://www.ncbi.nlm.nih.gov/pubmed/36983568
http://dx.doi.org/10.3390/jpm13030386