Structure-Based Virtual Screening of Furan-1,3,4-Oxadiazole Tethered N-phenylacetamide Derivatives as Novel Class of hTYR and hTYRP1 Inhibitors

Human tyrosinase (hTYR) is a key and rate-limiting enzyme along with human tyrosinase-related protein-1 (hTYRP1), which are among the most prominent targets of inhibiting hyper pigmentation and melanoma skin cancer. In the current in-silico computer-aided drug design (CADD) study, the structure-base...

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Detalles Bibliográficos
Autores principales: Irfan, Ali, Faisal, Shah, Ahmad, Sajjad, Al-Hussain, Sami A., Javed, Sadia, Zahoor, Ameer Fawad, Parveen, Bushra, Zaki, Magdi E. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059052/
https://www.ncbi.nlm.nih.gov/pubmed/36986444
http://dx.doi.org/10.3390/ph16030344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059052/
https://www.ncbi.nlm.nih.gov/pubmed/36986444
http://dx.doi.org/10.3390/ph16030344

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