Insights into In Vitro Adaptation of EV71 and Analysis of Reduced Virulence by In Silico Predictions

EV-A71 is a common viral pathogen that causes hand, foot and mouth disease. It is a single-stranded RNA virus that has a low fidelity RNA polymerase and, as a result, spontaneous mutations frequently occur in the EV-A71 genome. The mutations within the genome give rise to quasispecies within the vir...

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Detalles Bibliográficos
Autores principales: Koh, Jia Xuen, Masomian, Malihe, Anasir, Mohd Ishtiaq, Ong, Seng-Kai, Poh, Chit Laa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059274/
https://www.ncbi.nlm.nih.gov/pubmed/36992213
http://dx.doi.org/10.3390/vaccines11030629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059274/
https://www.ncbi.nlm.nih.gov/pubmed/36992213
http://dx.doi.org/10.3390/vaccines11030629

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