CRISPR/Cas9-Mediated Multi-Locus Promoter Engineering in ery Cluster to Improve Erythromycin Production in Saccharopolyspora erythraea

Erythromycins are a group of macrolide antibiotics produced by Saccharopolyspora erythraea. Erythromycin biosynthesis, which is a long pathway composed of a series of biochemical reactions, is precisely controlled by the type I polyketide synthases and accessary tailoring enzymes encoded by ery clus...

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Detalles Bibliográficos
Autores principales: Zhang, Xuemei, Wang, Yan, Zhang, Yue, Wang, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059589/
https://www.ncbi.nlm.nih.gov/pubmed/36985197
http://dx.doi.org/10.3390/microorganisms11030623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059589/
https://www.ncbi.nlm.nih.gov/pubmed/36985197
http://dx.doi.org/10.3390/microorganisms11030623

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