Acute ACAT1/SOAT1 Blockade Increases MAM Cholesterol and Strengthens ER-Mitochondria Connectivity

Cholesterol is a key component of all mammalian cell membranes. Disruptions in cholesterol metabolism have been observed in the context of various diseases, including neurodegenerative disorders such as Alzheimer’s disease (AD). The genetic and pharmacological blockade of acyl-CoA:cholesterol acyltr...

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Detalles Bibliográficos
Autores principales: Harned, Taylor C., Stan, Radu V., Cao, Ze, Chakrabarti, Rajarshi, Higgs, Henry N., Chang, Catherine C. Y., Chang, Ta Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059652/
https://www.ncbi.nlm.nih.gov/pubmed/36982602
http://dx.doi.org/10.3390/ijms24065525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059652/
https://www.ncbi.nlm.nih.gov/pubmed/36982602
http://dx.doi.org/10.3390/ijms24065525

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