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Integrated transcriptome and proteome analysis reveals posttranscriptional regulation of ribosomal genes in human brain organoids

During development of the human cerebral cortex, multipotent neural progenitors generate excitatory neurons and glial cells. Investigations of the transcriptome and epigenome have revealed important gene regulatory networks underlying this crucial developmental event. However, the posttranscriptiona...

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Detalles Bibliográficos
Autores principales: Sidhaye, Jaydeep, Trepte, Philipp, Sepke, Natalie, Novatchkova, Maria, Schutzbier, Michael, Dürnberger, Gerhard, Mechtler, Karl, Knoblich, Jürgen A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059687/
https://www.ncbi.nlm.nih.gov/pubmed/36989136
http://dx.doi.org/10.7554/eLife.85135