Structure Elucidation of Two Intriguing Neo-Debromoaplysiatoxin Derivatives from Marine Cyanobacterium Lyngbya sp. Showing Strong Inhibition of Kv1.5 Potassium Channel and Differential Cytotoxicity

Two aplysiatoxin derivatives, neo-debromoaplysiatoxin I (1) and neo-debromoaplysiatoxin J (2), were isolated from marine cyanobacterium Lyngbya sp. collected from the South China Sea. Their structures including absolute configurations were assigned by spectroscopic analysis, in combination with GIAO...

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Detalles Bibliográficos
Autores principales: Chen, Zijun, Chen, Na, Fu, Peng, Wang, Weiping, Bian, Shilin, Zhang, Huihui, Shen, Sicheng, Han, Bingnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059712/
https://www.ncbi.nlm.nih.gov/pubmed/36985758
http://dx.doi.org/10.3390/molecules28062786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059712/
https://www.ncbi.nlm.nih.gov/pubmed/36985758
http://dx.doi.org/10.3390/molecules28062786

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