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Natural Corynanthe-Type Cholinesterase Inhibitors from Malaysian Uncaria attenuata Korth.: Isolation, Characterization, In Vitro and In Silico Studies

The Uncaria genus is notable for its therapeutic potential in treating age-related dementia, such as Alzheimer’s disease. A phytochemical study of the leaves of Malaysian Uncaria attenuata Korth., afforded an undescribed natural corynanthe-type oxindole alkaloid, isovillocarine D (1) together with t...

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Detalles Bibliográficos
Autores principales: Chear, Nelson Jeng-Yeou, Ching-Ga, Tan Ai Fein, Khaw, Kooi-Yeong, León, Francisco, Tan, Wen-Nee, Yusof, Siti R., McCurdy, Christopher R., Murugaiyah, Vikneswaran, Ramanathan, Surash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059728/
https://www.ncbi.nlm.nih.gov/pubmed/36984830
http://dx.doi.org/10.3390/metabo13030390