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New Thienobenzo/Naphtho-Triazoles as Butyrylcholinesterase Inhibitors: Design, Synthesis and Computational Study

This study aims to test the inhibition potency of new thienobenzo/naphtho-triazoles toward cholinesterases, evaluate their inhibition selectivity, and interpret the obtained results by molecular modeling. The synthesis of 19 new thienobenzo/naphtho-triazoles by two different approaches resulted in a...

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Detalles Bibliográficos
Autores principales: Mlakić, Milena, Selec, Ida, Ćaleta, Irena, Odak, Ilijana, Barić, Danijela, Ratković, Ana, Molčanov, Krešimir, Škorić, Irena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059756/
https://www.ncbi.nlm.nih.gov/pubmed/36982951
http://dx.doi.org/10.3390/ijms24065879