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Colorectal Cancer Bioengineered Microtissues as a Model to Replicate Tumor-ECM Crosstalk and Assess Drug Delivery Systems In Vitro

Current 3D cancer models (in vitro) fail to reproduce complex cancer cell extracellular matrices (ECMs) and the interrelationships occurring (in vivo) in the tumor microenvironment (TME). Herein, we propose 3D in vitro colorectal cancer microtissues (3D CRC μTs), which reproduce the TME more faithfu...

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Detalles Bibliográficos
Autores principales: La Rocca, Alessia, De Gregorio, Vincenza, Lagreca, Elena, Vecchione, Raffaele, Netti, Paolo Antonio, Imparato, Giorgia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059762/
https://www.ncbi.nlm.nih.gov/pubmed/36982752
http://dx.doi.org/10.3390/ijms24065678