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Intrathecal Pseudodelivery of Drugs in the Therapy of Neurodegenerative Diseases: Rationale, Basis and Potential Applications

Intrathecal pseudodelivery of drugs is a novel route to administer medications to treat neurodegenerative diseases based on the CSF-sink therapeutic strategy by means of implantable devices. While the development of this therapy is still in the preclinical stage, it offers promising advantages over...

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Detalles Bibliográficos
Autores principales: Manuel, Menéndez-González, Tamba, Bogdan-Ionel, Leclere, Maxime, Mabrouk, Mostafa, Schreiner, Thomas-Gabriel, Ciobanu, Romeo, Cristina, Tomás-Zapico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059785/
https://www.ncbi.nlm.nih.gov/pubmed/36986629
http://dx.doi.org/10.3390/pharmaceutics15030768