Cardiac Functional and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder

CDKL5 (cyclin-dependent kinase-like 5) deficiency disorder (CDD) is a severe neurodevelopmental disease that mostly affects girls, who are heterozygous for mutations in the X-linked CDKL5 gene. Mutations in the CDKL5 gene lead to a lack of CDKL5 protein expression or function and cause numerous clin...

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Detalles Bibliográficos
Autores principales: Loi, Manuela, Bastianini, Stefano, Candini, Giulia, Rizzardi, Nicola, Medici, Giorgio, Papa, Valentina, Gennaccaro, Laura, Mottolese, Nicola, Tassinari, Marianna, Uguagliati, Beatrice, Berteotti, Chiara, Martire, Viviana Lo, Zoccoli, Giovanna, Cenacchi, Giovanna, Trazzi, Stefania, Bergamini, Christian, Ciani, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059787/
https://www.ncbi.nlm.nih.gov/pubmed/36982627
http://dx.doi.org/10.3390/ijms24065552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059787/
https://www.ncbi.nlm.nih.gov/pubmed/36982627
http://dx.doi.org/10.3390/ijms24065552

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