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Efficacy of Dolutegravir versus Darunavir in Antiretroviral First-Line Regimens According to Resistance Mutations and Viral Subtype

Background: Dolutegravir (DTG)-based first-line regimens have shown superior efficacy versus darunavir (DRV)-based ones in randomized trials. We compared these two strategies in clinical practice, particularly considering the role of pre-treatment drug resistance mutations (DRMs) and of the HIV-1 su...

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Detalles Bibliográficos
Autores principales: Salvo, Pierluigi Francesco, Farinacci, Damiano, Ciccullo, Arturo, Borghi, Vanni, Rusconi, Stefano, Saracino, Annalisa, Gennari, William, Bruzzone, Bianca, Vicenti, Ilaria, Callegaro, Annapaola, Di Biagio, Antonio, Zazzi, Maurizio, Di Giambenedetto, Simona, Borghetti, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059835/
https://www.ncbi.nlm.nih.gov/pubmed/36992471
http://dx.doi.org/10.3390/v15030762