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Product Validation and Stability Testing of Pharmacy Compounded Cholic Acid Capsules for Dutch Patients with Rare Bile Acid Synthesis Defects

Bile acid synthesis defects (BASDs) comprise a group of rare diseases that can be severely disabling. Bile acid supplementation with 5 to 15 mg/kg cholic acid (CA) has been hypothesized to decrease endogenous bile acid production, stimulate bile secretion, and improve bile flow and micellar solubili...

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Detalles Bibliográficos
Autores principales: Polak, Yasmin, Jacobs, Bart A. W., Bouwhuis, Natalja, Hollak, Carla E. M., Kroon, Maurice A. G. M., Kemper, Elles Marleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059964/
https://www.ncbi.nlm.nih.gov/pubmed/36986634
http://dx.doi.org/10.3390/pharmaceutics15030773