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A novel strategy to attenuate porcine reproductive and respiratory syndrome virus by inhibiting viral replication in the target pulmonary alveolar macrophages via hematopoietic-specific miR-142

Porcine reproductive and respiratory syndrome virus (PRRSV) is an economically important pathogen for the global pork industry. Although modified live virus (MLV) vaccines are commonly used for PRRSV prevention and control,  they still carry a risk of infecting the host and replicating in target cel...

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Detalles Bibliográficos
Autores principales: Tan, Shaoyuan, Wu, Weixin, Ge, Xinna, Zhang, Yongning, Han, Jun, Guo, Xin, Zhou, Lei, Yang, Hanchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060136/
https://www.ncbi.nlm.nih.gov/pubmed/37521530
http://dx.doi.org/10.1186/s44280-023-00002-2