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Characterizing brain dynamics during ketamine-induced dissociation and subsequent interactions with propofol using human intracranial neurophysiology

Ketamine produces antidepressant effects in patients with treatment-resistant depression, but its usefulness is limited by its psychotropic side effects. Ketamine is thought to act via NMDA receptors and HCN1 channels to produce brain oscillations that are related to these effects. Using human intra...

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Detalles Bibliográficos
Autores principales: Tian, Fangyun, Lewis, Laura D., Zhou, David W., Balanza, Gustavo A., Paulk, Angelique C., Zelmann, Rina, Peled, Noam, Soper, Daniel, Santa Cruz Mercado, Laura A., Peterfreund, Robert A., Aglio, Linda S., Eskandar, Emad N., Cosgrove, G. Rees, Williams, Ziv M., Richardson, R. Mark, Brown, Emery N., Akeju, Oluwaseun, Cash, Sydney S., Purdon, Patrick L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060225/
https://www.ncbi.nlm.nih.gov/pubmed/36991011
http://dx.doi.org/10.1038/s41467-023-37463-3