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Transgelin promotes lung cancer progression via activation of cancer-associated fibroblasts with enhanced IL-6 release

Cancer-associated fibroblasts (CAFs), the principal constituent of the heterogenous tumor microenvironment, have been shown to promote tumor progression; however, the underlying mechanism is still less clear. Here, we find that transgelin (TAGLN) protein levels increased in primary CAFs isolated fro...

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Detalles Bibliográficos
Autores principales: Sun, Chanjun, Zhang, Kaishang, Ni, Chen, Wan, Jiajia, Duan, Xixi, Lou, Xiaohan, Yao, Xiaohan, Li, Xiangnan, Wang, Ming, Gu, Zhuoyu, Yang, Pengyuan, Li, Zhenzhen, Qin, Zhihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060230/
https://www.ncbi.nlm.nih.gov/pubmed/36990991
http://dx.doi.org/10.1038/s41389-023-00463-5