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A-MYB and BRDT-dependent RNA Polymerase II pause release orchestrates transcriptional regulation in mammalian meiosis

During meiotic prophase I, spermatocytes must balance transcriptional activation with homologous recombination and chromosome synapsis, biological processes requiring extensive changes to chromatin state. We explored the interplay between chromatin accessibility and transcription through prophase I...

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Detalles Bibliográficos
Autores principales: Alexander, Adriana K., Rice, Edward J., Lujic, Jelena, Simon, Leah E., Tanis, Stephanie, Barshad, Gilad, Zhu, Lina, Lama, Jyoti, Cohen, Paula E., Danko, Charles G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060231/
https://www.ncbi.nlm.nih.gov/pubmed/36990976
http://dx.doi.org/10.1038/s41467-023-37408-w