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Abnormalities in intron retention characterize patients with systemic lupus erythematosus

Regulation of intron retention (IR), a form of alternative splicing, is a newly recognized checkpoint in gene expression. Since there are numerous abnormalities in gene expression in the prototypic autoimmune disease systemic lupus erythematosus (SLE), we sought to determine whether IR was intact in...

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Detalles Bibliográficos
Autores principales: Sun, Xiaoqian, Liu, Zhichao, Li, Zongzhu, Zeng, Zhouhao, Peng, Weiqun, Zhu, Jun, Zhao, Joel, Zhu, Chenghao, Zeng, Chen, Stearrett, Nathaniel, Crandall, Keith A., Bachali, Prathyusha, Grammer, Amrie C., Lipsky, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060252/
https://www.ncbi.nlm.nih.gov/pubmed/36991079
http://dx.doi.org/10.1038/s41598-023-31890-4