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Effect of scan-time shortening on the (11)C-PHNO binding potential to dopamine D(3) receptor in humans and test–retest reliability

OBJECTIVE: (11)C-PHNO is a PET radioligand most specific to dopamine D(3) receptor (D(3)R). The long scan duration of 120 min used in quantification of (11)C-PHNO binding to D(3)R in previous studies is challenging to subjects. The main objective of this study was to investigate the effects of short...

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Detalles Bibliográficos
Autores principales: Matsunaga, Keiko, Tonomura, Misato, Abe, Kohji, Shimosegawa, Eku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060283/
https://www.ncbi.nlm.nih.gov/pubmed/36656501
http://dx.doi.org/10.1007/s12149-022-01819-4