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Gα(i)-derived peptide binds the µ-opioid receptor

BACKGROUND: G protein-coupled receptors (GPCRs) transduce external stimuli into the cell by G proteins via an allosteric mechanism. Agonist binding to the receptor stimulates GDP/GTP exchange within the heterotrimeric G protein complex, whereas recent structures of GPCR–G protein complexes revealed...

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Detalles Bibliográficos
Autores principales: Kossoń, Piotr, Dyniewicz, Jolanta, Lipiński, Piotr F. J., Matalińska, Joanna, Misicka, Aleksandra, Bojarski, Andrzej J., Mordalski, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060287/
https://www.ncbi.nlm.nih.gov/pubmed/36840824
http://dx.doi.org/10.1007/s43440-023-00457-5