Interactions of fentanyl with blood platelets and plasma proteins: platelet sensitivity to prasugrel metabolite is not affected by fentanyl under in vitro conditions

BACKGROUND: Clinical trials indicate that fentanyl, like morphine, may impair intestinal absorption and thus decrease the efficacy of oral P2Y(12) inhibitors, such as clopidogrel, ticagrelor, and prasugrel. However, the ability of fentanyl to directly negate or reduce the inhibitory effect of P2Y(12...

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Detalles Bibliográficos
Autores principales: Bednarek, Radosław, Luzak, Boguslawa, Golański, Jacek, Boncler, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060303/
https://www.ncbi.nlm.nih.gov/pubmed/36646965
http://dx.doi.org/10.1007/s43440-023-00447-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060303/
https://www.ncbi.nlm.nih.gov/pubmed/36646965
http://dx.doi.org/10.1007/s43440-023-00447-7

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