Guanfacine inhibits interictal epileptiform events and sodium currents in prefrontal cortex pyramidal neurons

BACKGROUND: Guanfacine (an alpha-2A receptor agonist) is a commonly used drug with recognized efficacy in the treatment of attention deficit hyperactivity disorder (ADHD). This study aimed to assess the effects of guanfacine on short-lasting (interictal) epileptiform discharges in cortical neurons....

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Detalles Bibliográficos
Autores principales: Pasierski, Michał, Kołba, Weronika, Szulczyk, Bartłomiej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060326/
https://www.ncbi.nlm.nih.gov/pubmed/36800106
http://dx.doi.org/10.1007/s43440-023-00458-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060326/
https://www.ncbi.nlm.nih.gov/pubmed/36800106
http://dx.doi.org/10.1007/s43440-023-00458-4

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