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In vivo immunomodulation of IL6 signaling in a murine multiple trauma model

A significant number of trauma patients die during the ICU phase of care because of a severe immune response. Interleukin-6 (IL6) plays a central role within that immune response, signaling through a membrane-bound (IL6-R) and a soluble IL6 receptor (sIL6-R). IL6 and the sIL6-R can form an agonistic...

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Detalles Bibliográficos
Autores principales: Malysch, Tom, Reinhold, Jens Michael, Becker, Christopher A., Schmidt-Bleek, Katharina, Kleber, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060329/
https://www.ncbi.nlm.nih.gov/pubmed/36151360
http://dx.doi.org/10.1007/s12026-022-09319-3