Self assembling nanoparticle enzyme clusters provide access to substrate channeling in multienzymatic cascades

Access to efficient enzymatic channeling is desired for improving all manner of designer biocatalysis. We demonstrate that enzymes constituting a multistep cascade can self-assemble with nanoparticle scaffolds into nanoclusters that access substrate channeling and improve catalytic flux by orders of...

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Detalles Bibliográficos
Autores principales: Breger, Joyce C., Vranish, James N., Oh, Eunkeu, Stewart, Michael H., Susumu, Kimihiro, Lasarte-Aragonés, Guillermo, Ellis, Gregory A., Walper, Scott A., Díaz, Sebastián A., Hooe, Shelby L., Klein, William P., Thakur, Meghna, Ancona, Mario G., Medintz, Igor L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060375/
https://www.ncbi.nlm.nih.gov/pubmed/36990995
http://dx.doi.org/10.1038/s41467-023-37255-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060375/
https://www.ncbi.nlm.nih.gov/pubmed/36990995
http://dx.doi.org/10.1038/s41467-023-37255-9

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