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ACT001 inhibited CD133 transcription by targeting and inducing Olig2 ubiquitination degradation

Lung cancer is the most lethal malignancies with high aggressive and poor prognosis. Until now, the five-year survival rate has not been improved which brings serious challenge to human health. Lung cancer stem cells (LCSCs) serve as the root of cancer occurrence, progression, recurrence, and drug r...

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Detalles Bibliográficos
Autores principales: Deng, Huiting, Liu, Hailin, Yang, Guoyue, Wang, Dandan, Luo, Ying, Li, Chenglong, Qi, Zhenchang, Liu, Zhili, Wang, Peng, Jia, Yanfang, Gao, Yingtang, Ding, Yahui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060425/
https://www.ncbi.nlm.nih.gov/pubmed/36990974
http://dx.doi.org/10.1038/s41389-023-00462-6