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ACT001 inhibited CD133 transcription by targeting and inducing Olig2 ubiquitination degradation
Lung cancer is the most lethal malignancies with high aggressive and poor prognosis. Until now, the five-year survival rate has not been improved which brings serious challenge to human health. Lung cancer stem cells (LCSCs) serve as the root of cancer occurrence, progression, recurrence, and drug r...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060425/ https://www.ncbi.nlm.nih.gov/pubmed/36990974 http://dx.doi.org/10.1038/s41389-023-00462-6 |