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Locus coeruleus catecholamines link neuroticism and vulnerability to tau pathology in aging

Higher neuroticism is a risk factor for Alzheimer’s disease (AD), and is implicated in disordered stress responses. The locus coeruleus (LC)-catecholamine system is activated during perceived threat and is a centerpiece of developing models of the pathophysiology of AD, as it is the first brain regi...

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Detalles Bibliográficos
Autores principales:	Parent, Jourdan H., Ciampa, Claire J., Harrison, Theresa M., Adams, Jenna N., Zhuang, Kailin, Betts, Matthew J., Maass, Anne, Winer, Joseph R., Jagust, William J., Berry, Anne S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060440/ https://www.ncbi.nlm.nih.gov/pubmed/36191755 http://dx.doi.org/10.1016/j.neuroimage.2022.119658

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