Detrimental effects of soluble α-synuclein oligomers at excitatory glutamatergic synapses

INTRODUCTION: Oligomeric and fibrillar species of the synaptic protein α-synuclein are established key players in the pathophysiology of Parkinson’s disease and other synucleinopathies. Increasing evidence in the literature points to prefibrillar oligomers as the main cytotoxic species driving dysfu...

Descripción completa

Detalles Bibliográficos
Autores principales: Ferrari, Elena, Salvadè, Michela, Zianni, Elisa, Brumana, Marta, DiLuca, Monica, Gardoni, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060538/
https://www.ncbi.nlm.nih.gov/pubmed/37009450
http://dx.doi.org/10.3389/fnagi.2023.1152065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060538/
https://www.ncbi.nlm.nih.gov/pubmed/37009450
http://dx.doi.org/10.3389/fnagi.2023.1152065

Ejemplares similares