A Phase 1 randomized study on the safety and pharmacokinetics of OCS-05, a neuroprotective disease modifying treatment for Acute Optic Neuritis and Multiple Sclerosis

OCS-05 (aka BN201) is a peptidomimetic that binds to serum glucocorticoid kinase-2 (SGK2), displaying neuroprotective activity. The objective of this randomized, double-blind 2-part study was to test safety and pharmacokinetics of OCS-05 administered by intravenous (i.v.) infusion in healthy volunte...

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Detalles Bibliográficos
Autores principales: Villoslada, Pablo, Masso, Mar, Paris, Stephane, Hutchings, Simon, Koch, Annelize
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060579/
https://www.ncbi.nlm.nih.gov/pubmed/36991169
http://dx.doi.org/10.1038/s41598-023-32278-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060579/
https://www.ncbi.nlm.nih.gov/pubmed/36991169
http://dx.doi.org/10.1038/s41598-023-32278-0

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