Cargando…
A Phase 1 randomized study on the safety and pharmacokinetics of OCS-05, a neuroprotective disease modifying treatment for Acute Optic Neuritis and Multiple Sclerosis
OCS-05 (aka BN201) is a peptidomimetic that binds to serum glucocorticoid kinase-2 (SGK2), displaying neuroprotective activity. The objective of this randomized, double-blind 2-part study was to test safety and pharmacokinetics of OCS-05 administered by intravenous (i.v.) infusion in healthy volunte...
Autores principales: | Villoslada, Pablo, Masso, Mar, Paris, Stephane, Hutchings, Simon, Koch, Annelize |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060579/ https://www.ncbi.nlm.nih.gov/pubmed/36991169 http://dx.doi.org/10.1038/s41598-023-32278-0 |
Ejemplares similares
-
Neuroprotective Effects of Fingolimod in a Cellular Model of Optic Neuritis
por: Candadai, Amritha A., et al.
Publicado: (2021) -
Acute optic neuritis: Unmet clinical needs and model for new therapies
por: Galetta, Steven L., et al.
Publicado: (2015) -
Ipsilateral Uveitis and Optic Neuritis in Multiple Sclerosis
por: Thouvenot, Eric, et al.
Publicado: (2012) -
Optic neuritis as an early sign of multiple sclerosis
por: Kale, Nilufer
Publicado: (2016) -
Optic Neuritis as First Clinical Manifestations the Multiple Sclerosis
por: Halilovic, Emina Alimanovic, et al.
Publicado: (2014)