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Integrative analysis revealed that distinct cuprotosis patterns reshaped tumor microenvironment and responses to immunotherapy of colorectal cancer

BACKGROUND: Cuprotosis is a novel form of programmed cell death that involves direct targeting of key enzymes in the tricarboxylic acid (TCA) cycle by excess copper and may result in mitochondrial metabolic dysfunction. However, whether cuprotosis may mediate the tumor microenvironment (TME) and imm...

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Detalles Bibliográficos
Autores principales: Xu, Ximo, Ding, Chengsheng, Zhong, Hao, Qin, Wei, Shu, Duohuo, Yu, Mengqin, Abuduaini, Naijipu, Zhang, Sen, Yang, Xiao, Feng, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060625/
https://www.ncbi.nlm.nih.gov/pubmed/37006250
http://dx.doi.org/10.3389/fimmu.2023.1165101