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Integrative analysis revealed that distinct cuprotosis patterns reshaped tumor microenvironment and responses to immunotherapy of colorectal cancer
BACKGROUND: Cuprotosis is a novel form of programmed cell death that involves direct targeting of key enzymes in the tricarboxylic acid (TCA) cycle by excess copper and may result in mitochondrial metabolic dysfunction. However, whether cuprotosis may mediate the tumor microenvironment (TME) and imm...
Autores principales: | Xu, Ximo, Ding, Chengsheng, Zhong, Hao, Qin, Wei, Shu, Duohuo, Yu, Mengqin, Abuduaini, Naijipu, Zhang, Sen, Yang, Xiao, Feng, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060625/ https://www.ncbi.nlm.nih.gov/pubmed/37006250 http://dx.doi.org/10.3389/fimmu.2023.1165101 |
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