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Pan-cancer analysis identifies PD-L2 as a tumor promotor in the tumor microenvironment

BACKGROUND: Programmed cell death protein 1 (PD-1) receptor has two ligands,programmed death-ligand 1 (PD-L1) and PD-L2. When compared with PD-L1, PD-L2 has not received much attention, and its role remains unclear. METHODS: The expression profiles of pdcd1lg2 (PD-L2-encoding gene) mRNA and PD-L2 pr...

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Detalles Bibliográficos
Autores principales: Lv, Jingfang, Jiang, Zheng, Yuan, Junhu, Zhuang, Meng, Guan, Xu, Liu, Hengchang, Yin, Yefeng, Ma, Yiming, Liu, Zheng, Wang, Hongying, Wang, Xishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060638/
https://www.ncbi.nlm.nih.gov/pubmed/37006239
http://dx.doi.org/10.3389/fimmu.2023.1093716