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The role of demethylase AlkB homologs in cancer

The AlkB family (ALKBH1-8 and FTO), a member of the Fe (II)- and α-ketoglutarate-dependent dioxygenase superfamily, has shown the ability to catalyze the demethylation of a variety of substrates, including DNA, RNA, and histones. Methylation is one of the natural organisms’ most prevalent forms of e...

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Detalles Bibliográficos
Autores principales: Li, Qiao, Zhu, Qingsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060643/
https://www.ncbi.nlm.nih.gov/pubmed/37007161
http://dx.doi.org/10.3389/fonc.2023.1153463