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Autophagy and neurodegeneration: Unraveling the role of C9ORF72 in the regulation of autophagy and its relationship to ALS-FTD pathology

The proper functioning of the cell clearance machinery is critical for neuronal health within the central nervous system (CNS). In normal physiological conditions, the cell clearance machinery is actively involved in the elimination of misfolded and toxic proteins throughout the lifetime of an organ...

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Detalles Bibliográficos
Autores principales: Diab, Rim, Pilotto, Federica, Saxena, Smita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060823/
https://www.ncbi.nlm.nih.gov/pubmed/37006471
http://dx.doi.org/10.3389/fncel.2023.1086895