Treg-specific deletion of the phosphatase SHP-1 impairs control of inflammation in vivo

INTRODUCTION: To achieve a healthy and functional immune system, a delicate balance exists between the activation of conventional T cells (Tcon cells) and the suppression by regulatory T cells (Treg). The tyrosine phosphatase SHP-1, a negative regulator of TCR signaling, shapes this ‘activation-supp...

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Detalles Bibliográficos
Autores principales: Gu, QinLei, Tung, Kenneth S., Lorenz, Ulrike M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060847/
https://www.ncbi.nlm.nih.gov/pubmed/37006301
http://dx.doi.org/10.3389/fimmu.2023.1139326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060847/
https://www.ncbi.nlm.nih.gov/pubmed/37006301
http://dx.doi.org/10.3389/fimmu.2023.1139326

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