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Preclinical development of a first-in-class vaccine encoding HER2, Brachyury and CD40L for antibody enhanced tumor eradication

The induction of antiviral innate immunity by systemic immunization with live virus can be employed to positively impact the response to therapeutic vaccination. We previously demonstrated that systemic immunization with a non-replicating MVA encoding CD40 ligand (CD40L) enhances innate immune cell...

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Detalles Bibliográficos
Autores principales: Hinterberger, Maria, Endt, Kathrin, Bathke, Barbara, Habjan, Matthias, Heiseke, Alexander, Schweneker, Marc, Von Rohrscheidt, Julia, Atay, Cigdem, Chaplin, Paul, Kalla, Markus, Hausmann, Jürgen, Schmittwolf, Carolin, Lauterbach, Henning, Volkmann, Ariane, Hochrein, Hubertus, Medina-Echeverz, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060934/
https://www.ncbi.nlm.nih.gov/pubmed/36997583
http://dx.doi.org/10.1038/s41598-023-32060-2