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Preclinical development of a first-in-class vaccine encoding HER2, Brachyury and CD40L for antibody enhanced tumor eradication
The induction of antiviral innate immunity by systemic immunization with live virus can be employed to positively impact the response to therapeutic vaccination. We previously demonstrated that systemic immunization with a non-replicating MVA encoding CD40 ligand (CD40L) enhances innate immune cell...
Autores principales: | Hinterberger, Maria, Endt, Kathrin, Bathke, Barbara, Habjan, Matthias, Heiseke, Alexander, Schweneker, Marc, Von Rohrscheidt, Julia, Atay, Cigdem, Chaplin, Paul, Kalla, Markus, Hausmann, Jürgen, Schmittwolf, Carolin, Lauterbach, Henning, Volkmann, Ariane, Hochrein, Hubertus, Medina-Echeverz, José |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060934/ https://www.ncbi.nlm.nih.gov/pubmed/36997583 http://dx.doi.org/10.1038/s41598-023-32060-2 |
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