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Commercial influenza vaccines vary in HA-complex structure and in induction of cross-reactive HA antibodies

Influenza virus infects millions of people annually and can cause global pandemics. Hemagglutinin (HA) is the primary component of commercial influenza vaccines (CIV), and antibody titer to HA is a primary correlate of protection. Continual antigenic variation of HA requires that CIVs are reformulat...

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Detalles Bibliográficos
Autores principales: Myers, Mallory L., Gallagher, John R., Kim, Alexander J., Payne, Walker H., Maldonado-Puga, Samantha, Assimakopoulos, Haralabos, Bock, Kevin W., Torian, Udana, Moore, Ian N., Harris, Audray K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060936/
https://www.ncbi.nlm.nih.gov/pubmed/36997521
http://dx.doi.org/10.1038/s41467-023-37162-z